Paul Greengard (1925–2019)

Paul Greengard: Signals underlying moods, addictions, and brain disorders.

N owadays, whether people suffer from depression, mental health disorders, or addictions, medication can help. Researchers have learned how to fine tune the brain’s functions, often by targeting chemicals called neurotransmitters and the many signaling pathways through which they act. Although certain neurotransmitters had been identified more than 40 years ago, scientists knew relatively littl...

Art - Greengard (E)

The neostriatum is critically involved in the control of movement. The activity of neostriatal neurons is regulated by two major inputs: a glutamatergic input from the cortex and a dopaminergic input from the substantia nigra. Ionotropic glutamate receptors mediate synaptic transmission and plasticity in the neostriatum through intrinsic ligand-gated ion channels. In contrast, dopamine receptor...

پل کلودل Paul Claudel

Albert Benveniste , Paul Caspi , Paul

In this paper, we present a theory of synchronous data-ow languages. Our theory is supported by both some heuristic analysis of applications and some theoretical investigation of the data-ow paradigm. Our model covers both behavioural and operational aspects, and allows both synchronous and asynchronous styles of implementation for synchronous programs. This model served as a basis to establish...

Accelerating the Nonuniform Fast Fourier Transform ∗ Leslie Greengard

The nonequispaced Fourier transform arises in a variety of application areas, from medical imaging to radio astronomy to the numerical solution of partial differential equations. In a typical problem, one is given an irregular sampling of N data in the frequency domain and one is interested in reconstructing the corresponding function in the physical domain. When the sampling is uniform, the fa...